生物技术通报 ›› 2013, Vol. 0 ›› Issue (5): 22-27.

• 综述与专论 • 上一篇    下一篇

人酸性成纤维细胞生长因子的研究进展

谭亚清, 刘德虎   

  1. (中国农业科学院生物技术研究所,北京 100081)
  • 收稿日期:2012-11-22 修回日期:2013-05-24 出版日期:2013-05-24 发布日期:2013-05-24
  • 作者简介:谭亚清,女,硕士研究生,研究方向:植物分子生物学与基因工程;E-mail:tanyaqin.g@163.com
  • 基金资助:
    中国农业科学院生物技术研究所中央级公益性科研院所基本科研业务专项资助

The Prospect and Development of the Human Acid Fibroblast Growth Factor

Tan Yaqing, Liu Dehu   

  1. (Biotechnology Research Institute,Chinese Academy of Agricultural Sciences,Beijing 100081)
  • Received:2012-11-22 Revised:2013-05-24 Published:2013-05-24 Online:2013-05-24
  • About author:刘德虎,男,博士,研究员,研究方向:植物基因工程和植物生物反应器;E-mail:liudehu@public3.bta.net.cn

摘要: 成纤维细胞生长因子是一个大的蛋白质家族,人酸性成纤维细胞生长因子(human acidic fibroblast growth factor,haFGF)是其中的重要一员,具有广泛的生物学活性和潜在的临床应用价值。概述haFGF的结构、功能及其在基因工程方面的研究进展,并对haFGF在临床应用中可能存在的问题进行简单的探讨。

关键词: 人酸性成纤维细胞生长因子, 理化结构, 生物学功能, 临床应用, 基因工程

Abstract: Fibroblast growth factor is a large protein family, human acidic fibroblast growth factor is an important member of it, which has extensive biological functions and potential clinical value. In this paper we review the progress in the study on the structure, function and genetic engineering of human acidic fibroblast growth factor. Some prospects and problems about its application are also discussed.

Key words: Human acidic fibroblast growth factor, Physical and chemical structure, Biological function, Clinical application, Genetic engineering