Biotechnology Bulletin ›› 2017, Vol. 33 ›› Issue (1): 24-34.doi: 10.13560/j.cnki.biotech.bull.1985.2017.01.003

• Orignal Article • Previous Articles     Next Articles

Research Advance on Biosynthesis of Aromatic Amino Acids and Their Derivatives

SHEN Xiao-lin, YUAN Qi-peng   

  1. State Key Laboratory of Chemical Resource Engineering,Beijing Advanced Innovation Center for Soft Matter Science and Engineering,Beijing University of Chemical Technolog,Beijing 100029
  • Received:2016-12-10 Online:2017-01-25 Published:2017-01-19

Abstract: Bioengineering has been used to produce various of value-added products including fine chemicals,bulk chemicals,pharmaceuticals and nutraceuticals using sustainable materials. Synthetic biology is the foundation of bioengineering which combined functional genomics,computational biology with system biology to createnovel products and optimize bioprocess. In the past decades,many powerful tools developed from synthetic biology has been used in microorganisms,plants and animals. In this review,we summarize the synthesis of aromatic amino acids and its derivatives in microorganisms and review the recent advances in bio-production of value-added chemicals using synthetic biology.

Key words: synthetic biology, aromaticacids, flavonoids, organicacids, naturalproducts