Research Advances of Genetic Engineering of Microalgae for Improving Lipid Production

doi:10.13560/j.cnki.biotech.bull.1985.2015.04.010

Abstract

Abstract: In recent years, microalgae oil biodiesel has become a hot spot because of its strategic importance. Microalgae are a promising feedstock for biodiesel due to their short growth cycle, easy to mass culture, ability to absorb CO₂ and no taking farmland, etc. However, large-scale development and utilization of microalgae biomass energy is limited by less knowledge about metabolic mechanisms of lipid synthesis and lagging research of genome in microalgae. With the development of modern biotechnology, improving lipid content and biomass of microalgae may achieve through genetic engineering and metabolic engineering methods. This review describes recent efforts to metabolic mechanisms on lipid biosynthesis and genetic engineering techniques on increasing lipid content, which provide technical reserves for attaining high lipid transgenic microalgae and producing microalgae biodiesel.

Key words: microalgae, genetic engineering, biodiesel, lipid

Li Yi, Wang Chaogang, Hu Zhangli. Research Advances of Genetic Engineering of Microalgae for Improving Lipid Production[J]. Biotechnology Bulletin, 2015, 31(3): 70-81.

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