Effects of ANGPTL4 on Intestinal Microbiota Affecting Lipid Metabolism of Animals

doi:10.13560/j.cnki.biotech.bull.1985.2020-0028

Abstract

Abstract: Angiopoietin-like protein 4（ANGPTL4）is a protein that is closely related to animal lipid metabolism and widely expressed in many tissues of animals. It is recognized as an important medium to communicate intestinal microbiota and host lipid metabolism. This article summarizes the relationship between gut microbes and host fat deposition,the effect of gut microbes on host ANGPTL4,the role of ANGPTL4 on animal lipid metabolism,and the relationship among gut microbes,ANGPTL4 and animal lipid metabolism. Also this article discusses the significance and existing issues in studying intestinal microbiota affecting lipid metabolism of animals via ANGPTL4,aiming at providing a better explanation for the effects of feed additives such as probiotics and acidifiers on fat deposition and production performance of livestock and poultry.

Key words: angiopoietin-like protein 4, intestinal microbiota, lipid metabolism

ZHAO Xu, XU Qun, HOU Yan-ru, LI Ming-yu, ZHANG Ya-ning, WANG Hai. Effects of ANGPTL4 on Intestinal Microbiota Affecting Lipid Metabolism of Animals[J]. Biotechnology Bulletin, 2020, 36(6): 230-235.

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