Research Progress of Clostridium cellulovorans Cellulosome

Abstract

Abstract: Cellulose, the main structural component of plant cell walls, is extremely difficult degrade. Cellulases play an important role in the degradation of cellulosic materials, which have been found either as free enzymes or as a large extracellular enzyme complex called the cellulosome. Cellulosomes consist of non-enzymatic scaffolding protein（s）and cellulosomal enzyme subunits. The scaffolding protein contains cohesins for the cellulosomal enzyme subunits which have various defferent functions and invariably contain a cohesin-binding site named dockerin. The composition, function, and gene cluster of Clostridium cellulovorans cellulosome were reviewed here, and the research advances in biotechnology were also summarized, aiming to provide some basic information for the studies of other cellulosomes, the constructions of minicellulosomes with precise functions and the applications in biotechnology.

Key words: Cellulosome, Clostridium cellulovorans, Scaffoldin, Cellulosomal enzyme, Gene cluster, Expression regulation

Li Junxia, Zhang Rijun, Chen Dongdong. Research Progress of Clostridium cellulovorans Cellulosome[J]. Biotechnology Bulletin, 2013, 0(3): 37-43.

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