Biotechnology Bulletin ›› 2017, Vol. 33 ›› Issue (10): 40-45.doi: 10.13560/j.cnki.biotech.bull.1985.2017-0725

• Review • Previous Articles     Next Articles

Research Progress of New Biomarker Gene of phoH for Bacteriophage Genetic Diversity

LI Xiang1,2, SUN Yan1,2, WANG Xin-zhen3, LIU Jun-jie1, WANG Guang-hua1   

  1. 1. Key Laboratory of Mollisols Agroecology,Northeast Institute of Geography and Agroecology,Chinese Academy of Sciences,Harbin 150081
    2. University of Chinese Academy of Sciences,Beijing 100049
    3. Key Laboratory of Agricultural Water Resources,Center for Agricultural Resources Research,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Shijiazhuang 050021
  • Received:2017-09-01 Online:2017-10-29 Published:2017-10-29
  • Contact: 王光华,男,博士,研究员,研究方向:微生物生态;E-mail:wanggh@iga.ac.cn

Abstract: Bacteriophages(phages)are the simplest biological entities,which play important roles not only in the regulation of their host communities and horizontal transfer of genetic materials,but also in the element biogeochemical cycles. Although the importance of phages is increasingly being paid attentions by researchers,however there are still great limitations on the study of phage gene diversity until now. Therefore,the work of finding and verification of a suitable molecular marker gene for studying the genetic diversity of phage in natural environments is one of the hotspots of virus ecology. In this paper,a new molecular biomarker gene of phage auxiliary metabolic gene of phoH was introduced,and the recent advances in using this gene to reveal the phage genetic diversity in marine waters,paddy floodwaters and desert hypoliths are reviewed. Results showed that the distribution of phage phoH gene was closely related to its living environments,and phoH clones were divided into several groups according their obtained environments. In the end of the paper,the future research directions of phage phoH gene are also proposed.

Key words: bacteriophage, phoH gene, diversity, marine, paddy field